Jeffrey D. Mosko

MD, MSc, FRCPC

Investigator

Biography

Dr. Jeffrey Mosko is a Clinician in Quality and Innovation (CQI) in the Division of Gastroenterology at St. Michael’s Hospital and an Assistant Professor of Medicine in in the Department of Medicine at the University of Toronto. He serves as the gastroenterology divisional director of postgraduate education at St. Michael’s Hospital. He graduated with a BSc and then MD from the University of Western Ontario. He completed his internal medicine and general gastroenterology training at the University of Toronto. He then completed his fellowship training in advanced endoscopy at Beth Israel Deaconess Medical Center and Harvard Medical School in Boston, Massachusetts and has been on staff at St. Michael’s Hospital in Toronto since that time. He completed an MSc in Quality Improvement and Patient Safety at the Institute of Health Policy, Management and Evaluation at the University of Toronto and continues to teach in the MSc program there. He serves as a co-director of the advanced endoscopy fellowship at St. Michael’s Hospital and the International Course on Therapeutic Endoscopy.

Dr. Mosko’s research is in quality improvement in endoscopy. He has led local initiatives to improve sedation for advanced endoscopic procedures, management of acute pancreatitis and the patient experience in endoscopy, among others. He is leading provincial/national initiatives to improve access to endoscopic ultrasound, colonoscopy skills and polypectomy technique. Finally, he is collaborating on an international scale to translate best practices to meaningful quality measures.

Recent Publications

  1. Khalaf, K, May, GR, Mosko, JD. Response to 'Rectal versus colonic submucosal cancer rates and procedural outcomes in large non-pedunculated polyps: French ESD registry data'. Gut. 2025; :. doi: 10.1136/gutjnl-2025-337470. PubMed PMID:41381177 .
  2. Khalaf, K, Hanna, Y, Nishimura, T, Li, H, Calo, NC, May, GR et al.. Risk stratification for stricture formation after endoscopic submucosal dissection for esophageal dysplasia. Dis Esophagus. 2025;38 (6):. doi: 10.1093/dote/doaf096. PubMed PMID:41182790 PubMed Central PMC12581832.
  3. Bucheeri, MAGA, Khalaf, K, Li, H, Yuan, Y, Tham, D, Jayawardena, R et al.. Prevalence and impact of sarcopenia in chronic pancreatitis: A systematic review and meta-analysis. Pancreatology. 2025;25 (7):1062-1070. doi: 10.1016/j.pan.2025.09.026. PubMed PMID:40998620 .
  4. Yang, D, Robalino Gonzaga, E, Hasan, MK, Trindade, AJ, Radlinski, M, Burbridge, RA et al.. Minimum standards for training in colorectal endoscopic mucosal resection among advanced endoscopy trainees. Endosc Int Open. 2025;13 :a26839906. doi: 10.1055/a-2683-9906. PubMed PMID:40978021 PubMed Central PMC12445247.
  5. Scaffidi, MA, Khalaf, K, Pawlak, KM, Chopra, D, Tham, D, Na, C et al.. Factors affecting technical success of endoscopic retrograde cholangiopancreatographic outcomes in patients with surgically altered foregut anatomy: a retrospective study. J Can Assoc Gastroenterol. 2025;8 (4):136-141. doi: 10.1093/jcag/gwaf010. PubMed PMID:40900918 PubMed Central PMC12400998.
  6. Medawar, E, Pohl, H, Rex, DK, Levenick, JM, Pleskow, DK, Khashab, MA et al.. Adverse events of cold snare compared with hot snare and ablation endoscopic mucosal resection for large colorectal polyps. Endoscopy. 2025; :. doi: 10.1055/a-2665-0521. PubMed PMID:40719106 .
  7. Dang, F, Kwon, J, Lin, A, Banerjee, S, McCracken, T, Tavangar, A et al.. The potential utility of CHATGPT4.0 as an AI assistant in the education and management of patients with Barrett's esophagus. Dis Esophagus. 2025;38 (4):. doi: 10.1093/dote/doaf050. PubMed PMID:40623317 PubMed Central PMC12233505.
  8. Fujiyoshi, Y, Khalaf, K, Tham, D, Fujiyoshi, MRA, Streutker, CJ, Calo, NC et al.. Endoscopic mucosal resection for Barrett's neoplasia: Long-term outcomes from the largest Canadian single-center experience. Endosc Int Open. 2025;13 :a26028961. doi: 10.1055/a-2602-8961. PubMed PMID:40611834 PubMed Central PMC12223934.
  9. Medawar, E, Taghiakbari, M, Djinbachian, R, Shahidi, N, Levenick, J, Mosko, JD et al.. Safety and efficacy of margin and base ablation after endoscopic mucosal resection of large nonpedunculated colorectal polyps: a prospective multicenter study. Gastrointest Endosc. 2025; :. doi: 10.1016/j.gie.2025.05.034. PubMed PMID:40513805 .
  10. Zheng, K, Khalaf, K, Li, H, Mosko, JD, May, GR, Calo, NC et al.. Technical success of double-balloon enteroscopy - Endoscopic retrograde cholangiopancreatography in patients with pancreaticojejunostomy anastomotic strictures post-pancreatoduodenectomy. Pancreatology. 2025;25 (4):600-601. doi: 10.1016/j.pan.2025.04.013. PubMed PMID:40328551 .
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