Research Programs

Biography

Research Interests

Multiple sclerosis (MS), MRI biomarkers with clinical utility in prognostication and disease monitoring, cohort studies

Research Activities

Jiwon Oh is a staff neurologist, scientist, and Medical Director of the Barlo Multiple Sclerosis (MS) Program at St. Michael’s Hospital, University of Toronto. Dr. Oh’s research focuses on developing advanced MRI techniques in the spinal cord and brain for use in clinical settings. She leads the MRI research program at St. Michael’s Hospital, and is the principal investigator on numerous local and multi-center collaborative studies, including the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo), which is a national prospective cohort study designed to better understand progression in MS.

Recent Publications

  1. Toljan, K, Oh, J, Ontaneda, D. 2024 Diagnostic Criteria for Multiple Sclerosis-A Unified Approach. JAMA Neurol. 2025; :. doi: 10.1001/jamaneurol.2025.4243. PubMed PMID:41212567 .
  2. Sawicka, KM, Feldman, BM, Banwell, B, Beyene, J, Cragg, JJ, Bar-Or, A et al.. A cross-sectional study investigating age of multiple sclerosis onset and its association with self-management knowledge and behaviors. Mult Scler Relat Disord. 2025;104 :106816. doi: 10.1016/j.msard.2025.106816. PubMed PMID:41175530 .
  3. Hu, F, Ren, Z, Chen, L, Valcarcel, AM, Dworkin, J, Renner, B et al.. Automated segmentation of multiple sclerosis lesions, paramagnetic rims, and central vein sign on MRI provides reliable diagnostic biomarkers. Imaging Neurosci (Camb). 2025;3 :. doi: 10.1162/IMAG.a.932. PubMed PMID:41089191 PubMed Central PMC12516162.
  4. Barkhof, F, Reich, DS, Oh, J, Rocca, MA, Li, DKB, Sati, P et al.. 2024 MAGNIMS-CMSC-NAIMS consensus recommendations on the use of MRI for the diagnosis of multiple sclerosis. Lancet Neurol. 2025;24 (10):866-879. doi: 10.1016/S1474-4422(25)00304-7. PubMed PMID:40975102 .
  5. Montalban, X, Lebrun-Frénay, C, Oh, J, Arrambide, G, Moccia, M, Pia Amato, M et al.. Diagnosis of multiple sclerosis: 2024 revisions of the McDonald criteria. Lancet Neurol. 2025;24 (10):850-865. doi: 10.1016/S1474-4422(25)00270-4. PubMed PMID:40975101 .
  6. Phillips, B, Morrow, SA, Singh, H, Oh, J, Kolind, S, Lynd, LD et al.. Machine learning using clinical variables to screen for depression and anxiety in people with early multiple sclerosis. Mult Scler Relat Disord. 2025;104 :106761. doi: 10.1016/j.msard.2025.106761. PubMed PMID:40975017 .
  7. Suthiphosuwan, S, Lim, TR, Hu, Z, Colak, E, Lee, LE, Guenette, M et al.. Choroid plexus enlargement correlates with demyelinating lesions and thalamic atrophy in radiologically isolated syndrome. Mult Scler. 2025;31 (11):1314-1325. doi: 10.1177/13524585251375365. PubMed PMID:40970552 .
  8. Shipley, J, Beadnall, HN, Sanfilippo, PG, Yeh, WZ, Horakova, D, Havrdova, EK et al.. Pregnancy-Related Disease Outcomes in Women With Moderate to Severe Multiple Sclerosis Disability. JAMA Netw Open. 2025;8 (9):e2531581. doi: 10.1001/jamanetworkopen.2025.31581. PubMed PMID:40952740 PubMed Central PMC12439057.
  9. Renner, B, Verter, ED, Absinta, M, Daboul, L, Raza, P, Martin, ML et al.. Frequency and Diagnostic Implications of Paramagnetic Rim Lesions in People Presenting for Diagnosis to a Multiple Sclerosis Clinic. Neurology. 2025;105 (6):e213912. doi: 10.1212/WNL.0000000000213912. PubMed PMID:40893055 PubMed Central PMC12596004.
  10. Kever, A, Kang, N, Meza, C, Pogacar, M, Lui, R, Hennessy, K et al.. Not for everyone: examining predictors of cognitive rehabilitation success in multiple sclerosis. J Neurol. 2025;272 (9):593. doi: 10.1007/s00415-025-13345-0. PubMed PMID:40858802 .
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Affiliations & Other Activities

  • Staff Neurologist, Division of Neurology, Department of Medicine, St. Michael’s Hospital
  • Associate Professor, Department of Medicine, University of Toronto
  • Adjunct Faculty, Department of Neurology, Johns Hopkins University