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Aaron Nauth

MD, MSc

Scientist

Email: Aaron.Nauth@unityhealth.to
Tel: 416-864-6003

Research Programs

Biography

I have an active basic science laboratory at the Keenan Research Centre for Biomedical Science that is focused on investigating the use of stem cell therapies for the augmentation of bone and tendon healing. Research activities in this musculoskeletal research laboratory are co-supervised with Dr. Emil Schemitsch. We have two active lines of research including the investigation of cell and tissue engineering strategies for fracture healing and healing of the rotator cuff. I also have a strong interest in clinical research with a particular focus on randomized clinical trials in orthopedic trauma and sports medicine.

Recent Publications

  1. Bzovsky, S, O'Hara, NN, Slobogean, GP, Sprague, S, Axelrod, DE, Hoit, G et al.. Revisiting the FAITH Trial: A Secondary Analysis Yielding Novel Insights with the Win Ratio. JB JS Open Access. 2025;10 (4):. doi: 10.2106/JBJS.OA.25.00230. PubMed PMID:41281368 PubMed Central PMC12637341.
  2. Khan, JS, Mulazzani, F, Devereaux, PJ, Bhandari, M, Guerra-Farfan, E, Patel, A et al.. Pain as a Driver of Myocardial Injury in Hip Fracture Patients: A Hip Fracture Accelerated Surgical Treatment and Care Track (HIP ATTACK) Trial Secondary Analysis. Anesthesiology. 2025; :. doi: 10.1097/ALN.0000000000005818. PubMed PMID:41147656 .
  3. Schemitsch, GW, Lameire, DL, Hoit, G, Vyas, M, Khoshbin, A, Fowler, R et al.. Predictors of Conversion Total Hip Arthroplasty After Surgically Managed Acetabulum Fractures: A Prognostic Factor Systematic Review and Meta-Analysis. JBJS Rev. 2025;13 (8):. doi: 10.2106/JBJS.RVW.25.00086. PubMed PMID:40779655 .
  4. Mercier, MR, Broderick, JM, Hibberd, CS, Russell, SP, Halai, MM, Atrey, A et al.. Failure of the Noncontact Bridging Periprosthetic Plating System: A Single-Institution Experience. Arthroplast Today. 2025;34 :101753. doi: 10.1016/j.artd.2025.101753. PubMed PMID:40641829 PubMed Central PMC12241400.
  5. Raleigh, M, Gagnon, S, Felice, H, Godbout, CA, Halai, MM, Atrey, A et al.. The use of bone morphogenetic protein-2 compared with platelet-derived growth factor for the treatment of nonunion : a comparative investigation in a small animal critical-sized defect model. Bone Joint J. 2025;107-B (7):744-751. doi: 10.1302/0301-620X.107B7.BJJ-2024-1127.R1. PubMed PMID:40588262 .
  6. Dehghan, N, McGraw-Heinrich, J, Schemitsch, C, Nauth, A, Hidy, J, Vicente, M et al.. Operative Treatment of Flail Chest Injuries Does Not Reduce Pain or In-Hospital Opioid Requirements: Results from a Multicenter Randomized Controlled Trial. J Bone Joint Surg Am. 2025;107 (9):928-935. doi: 10.2106/JBJS.24.01099. PubMed PMID:40053576 .
  7. Sun, H, Godbout, C, Ryan, G, Ali, I, Higgins, J, Hoit, G et al.. The Effects of Antibiotic-Impregnated Spacers on Bone Healing in an Animal Model of the Induced Membrane Technique: Healing of a Critical-Size Femoral Defect in a Rat Model. JB JS Open Access. 2025;10 (1):. doi: 10.2106/JBJS.OA.24.00059. PubMed PMID:39991111 PubMed Central PMC11841848.
  8. Hali, K, Gagnon, S, Raleigh, M, Ali, I, Sniderman, J, Halai, M et al.. The Effect of Cryopreservation on the Bone Healing Capacity of Endothelial Progenitor Cells in a Bone Defect Model. J Orthop Res. 2025;43 (5):904-911. doi: 10.1002/jor.26051. PubMed PMID:39888074 .
  9. Hoit, G, Chahal, J, Khan, R, Rubacha, M, Nauth, A, Whelan, DB et al.. Early Compared with Delayed Reconstruction in Multiligament Knee Injury: A Retrospective Propensity Analysis. J Bone Joint Surg Am. 2024;106 (20):1903-1909. doi: 10.2106/JBJS.23.00795. PubMed PMID:39172809 .
  10. Borges, FK, Guerra-Farfan, E, Bhandari, M, Patel, A, Slobogean, G, Feibel, RJ et al.. Myocardial Injury in Patients with Hip Fracture: A HIP ATTACK Randomized Trial Substudy. J Bone Joint Surg Am. 2024;106 (24):2303-2312. doi: 10.2106/JBJS.23.01459. PubMed PMID:39052767 .
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Affiliations & Other Activities

  • Staff Surgeon, Division of Orthopedic Surgery, St. Michael’s Hospital
  • Assistant Professor, Orthopedic Surgery, University of Toronto
  • Consulting Staff, Orthopedic Surgery, Sunnybrook Health Sciences Centre
  • Consulting Staff, Orthopedic Surgery, Women’s College Hospital