Corinne E. Fischer

MD

Investigator

Research Programs

Biography

Dr. Fischer is a staff psychiatrist with the Mental Health Service at St. Michael’s Hospital and director of Geriatric Psychiatry at St. Michael’s Hospital, Unity Health. She is an associate scientist and co-director of Neurodegenerative Research, Division of Neuroscience Research, at the Keenan Research Centre for Biomedical Science, the Li Ka Shing Knowledge Institute, St. Michael’s Hospital, Toronto, Canada. She has an academic appointment as Associate Professor at the University of Toronto in the Division of Geriatric Psychiatry and is a full member of the Institute of Medical Science where she supervises graduate students, research fellows, residents and medical students. She is an associate editor of the Journal of Alzheimer’s disease and immediate past academic co-chair of the Neuropsychiatric Symptom Professional Interest Area ISTAART in addition to being a member of several national/international organizations including CAGP, AAGP, IPA and ISTAART.  Dr. Fischer’s main clinical and research focus centres around neuropsychiatric symptoms in Alzheimer’s disease and their clinical, imaging and pathological correlates. She is a principal investigator for a number of peer-reviewed and industry sponsored grants, including a multi-centred study of photobiomodulation therapy in moderate to severe Alzheimer’s disease.

Recent Publications

  1. Azami, H, McAndrews, MP, Rostaghi, M, Zomorrodi, R, Brooks, H, Blumberger, DM et al.. Multiscale dispersion entropy of resting-state EEG in older adults with Alzheimer's disease, mild cognitive impairment, and remitted major depressive disorder. J Alzheimers Dis. 2025; :13872877251410962. doi: 10.1177/13872877251410962. PubMed PMID:41470021 .
  2. Pavlidis, DI, Rionda, MA, Fischer, CE, Jennings, MA, Sinko, DS, Vats, B et al.. MAP hydrogel promotes revascularization of human ovarian graft and integration with the hypothalamic-pituitary axis in a mouse model of primary ovarian insufficiency. bioRxiv. 2025; :. doi: 10.64898/2025.12.08.693003. PubMed PMID:41427366 PubMed Central PMC12713597.
  3. Ismail, Z, Guan, DX, Babulal, GM, Bateman, JR, Cantillon, M, Creese, B et al.. Plasma biomarkers in neuropsychiatric syndromes: A narrative review. J Alzheimers Dis. 2026;109 (1):44-69. doi: 10.1177/13872877251392185. PubMed PMID:41284585 PubMed Central PMC12722585.
  4. Choudhury, S, Colman, S, Chu, L, Davies, SJC, Derkach, P, Elmi, S et al.. Sex Differences in Phenomenology of Behavioral and Psychological Symptoms of Dementia. Neurodegener Dis. 2025; :1-11. doi: 10.1159/000548713. PubMed PMID:41037500 .
  5. Vyas, MV, de Oliveira, C, Saposnik, G, Austin, PC, Yu, AY, Haldenby, O et al.. Increased risk of suicide after stroke: A population-based matched cohort study. Int J Stroke. 2025; :17474930251379165. doi: 10.1177/17474930251379165. PubMed PMID:40913243 .
  6. Namasivayam, AA, Fischer, CE, Abler, V, Creese, B, Gastiazoro, MP, Hermida, AP et al.. Recommendations for management and future investigation of psychosis in neurodegenerative disease: Findings from the International Psychogeriatric Association (IPA) working group. Int Psychogeriatr. 2025; :100133. doi: 10.1016/j.inpsyc.2025.100133. PubMed PMID:40835496 .
  7. Shwab, EK, Pathak, GA, Harvey, J, Belloy, ME, Fischer, CE, Lutz, MW et al.. Leveraging multiomic approaches to elucidate mechanisms of heterogeneity in Alzheimer's disease: Neuropsychiatric symptoms, co-pathologies, and sex differences. Alzheimers Dement. 2025;21 (8):e70549. doi: 10.1002/alz.70549. PubMed PMID:40823789 PubMed Central PMC12359071.
  8. Keng, A, Kapustin, D, Ma, C, Bingham, KS, Fischer, CE, Mah, L et al.. Neuropsychiatric Symptoms Present Differently in Individuals with Different High-Risk States of Dementia. Dement Geriatr Cogn Disord. 2025; :1-12. doi: 10.1159/000547061. PubMed PMID:40562015 PubMed Central PMC12503446.
  9. Lawson, RP, Zomorrodi, R, Joseph, M, Alhabbal, H, Asare, G, Blumberger, DM et al.. Assessing Motor Cortex Excitability and Its Relationship with Cortical Atrophy in Alzheimer's Dementia. Can J Neurol Sci. 2025; :1-8. doi: 10.1017/cjn.2025.79. PubMed PMID:40485143 .
  10. Alhamdah, Y, Yan, E, Butris, N, Kapoor, P, Lovblom, LE, Rajji, TK et al.. Depression in older surgical patients: a multicentre prospective longitudinal study. Br J Anaesth. 2025; :. doi: 10.1016/j.bja.2025.04.016. PubMed PMID:40404498 .
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Affiliations & Other Activities

  • Director of Geriatric Psychiatry, Psychiatry, St. Michael’s Hospital
  • Director of Memory Disorders Clinic, Psychiatry, St. Michael’s Hospital
  • Director of the Geriatric Mental Health Outreach Program, Psychiatry, St. Michael’s Hospital
  • Associate Professor, Department of Psychiatry, University of Toronto
  • Associate Member, IMS