David Jenkins

OC, MD, FRSC, FRCP, FRCPC, PhD, DSc

Scientist

Biography

Educated at Oxford University, Dr. David Jenkins is currently a Professor in both the Departments of Nutritional Sciences and Medicine, Faculty of Medicine, University of Toronto, a Staff Physician in the Division of Endocrinology and Metabolism, the Director of the Clinical Nutrition and Risk Factor Modification Center, and a Scientist in the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. He has served on committees in Canada and the United States that have formulated nutritional guidelines for the treatment of diabetes and recommendations for fibre and macronutrient intake (fat protein and carbohydrates) for the general population (including the Dietary Reference intake or DRIs) under the joint United States-Canada DRI system (RDAs) of the National Academy of Sciences (Washington, DC). He led the team that first defined and explored the concept of the glycemic index of foods. He was the first to demonstrate the breadth of metabolic effects of viscous soluble fiber (as found in fruit, certain beans, oats barley) on blood glucose and cholesterol lowering of relevance to prevention and treatment of diabetes and heart disease. His studies on combining cholesterol lowering food components (dietary portfolio) have been recognized as creating an effective dietary alternative to drug therapy (statins) for lower risk people. In an important study, he compared a dietary portfolio with all food provided with a statin in the same people and demonstrated that the effects of both were comparable. The dietary portfolio, on the basis of this and other studies including a major cross Canada real world study, was the only dietary approach referenced in 2004 Guidelines update of the US National Cholesterol Education Program (ATP III) and recommended in the Canadian Cardiovascular Society (CCS) guidelines for 2012 and the European Atherosclerosis Society consensus statement (2015). He has received many National and International awards in recognition of his contribution to nutrition research. He believes in the value of plant based diets, and that a major effort is required to mount large studies to determine the extent of their health benefits. He also believes that diets have to be environmentally sustainable.

Please note: Dr. Jenkins is currently accepting volunteer students.

Recent Publications

  1. Sievenpiper, JL, Jenkins, DJ, Chiavaroli, L. Fewer bites of beef to make an impact: even small changes toward a more sustainable diet and lifestyle can meet personal and public health goals while addressing planetary health. Am J Clin Nutr. 2025;122 (4):903-906. doi: 10.1016/j.ajcnut.2025.07.022. PubMed PMID:41043872 PubMed Central PMC12674048.
  2. Hosseini, B, Condon, A, da Costa, BR, Daley, P, Greiver, M, Jüni, P et al.. Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings. BMJ Open. 2025;15 (8):e097134. doi: 10.1136/bmjopen-2024-097134. PubMed PMID:40754325 PubMed Central PMC12320028.
  3. Esposito, G, Augustin, LSA, Jenkins, DJA, Ferraroni, M, Parazzini, F, Crispo, A et al.. Adherence to a Cholesterol-Lowering Diet and the Risk of Female Hormone-Related Cancers: An Analysis From a Case-Control Study Network. BJOG. 2025;132 (12):1791-1801. doi: 10.1111/1471-0528.18302. PubMed PMID:40677090 .
  4. Wiedenroth, CB, Jenkins, D, Brenot, P, Lang, IM, Matsubara, H, Pepke-Zaba, J et al.. Management of chronic thromboembolic pulmonary hypertension. J Heart Lung Transplant. 2025;44 (7S):S8-S14. doi: 10.1016/j.healun.2025.02.1691. PubMed PMID:40653350 .
  5. Chon, JE, Lai, KZH, Semnani-Azad, Z, Metherel, AH, Jenkins, DJA, Bazinet, RP et al.. Omega-3 Polyunsaturated Fatty Acids and Adipose Tissue Inflammation in Humans: A Scoping Review. Nutr Rev. 2025; :. doi: 10.1093/nutrit/nuaf089. PubMed PMID:40631936 .
  6. Kavanagh, ME, Zurbau, A, Glenn, AJ, Oguntala, JO, Josse, RG, Malik, VS et al.. The portfolio dietary pattern and risk of cardiovascular disease mortality during 1988-2019 in US adults: a prospective cohort study. BMC Med. 2025;23 (1):287. doi: 10.1186/s12916-025-04067-1. PubMed PMID:40394599 PubMed Central PMC12093672.
  7. Chen, V, Chiavaroli, L, Glenn, AJ, Kavanagh, ME, Zeitoun, T, Mahdavi, S et al.. Portfolio diet and LDL-C in a young, multiethnic cohort: cross-sectional analyses with cumulative exposure modeling. BMC Public Health. 2025;25 (1):1761. doi: 10.1186/s12889-025-22479-9. PubMed PMID:40361017 PubMed Central PMC12070585.
  8. Rossi, A, Chen, ZH, Ahmadiankalati, M, Campisi, SC, Reyna, ME, Dempsey, K et al.. Determining the interplay of prenatal parental BMI in shaping child BMI trajectories: the CHILD Cohort Study. Int J Obes (Lond). 2025;49 (8):1608-1615. doi: 10.1038/s41366-025-01792-8. PubMed PMID:40355590 .
  9. Mahdavi, S, Rosychuk, K, Jenkins, DJA, Percy, AJ, Borchers, CH, El-Sohemy, A et al.. Multiomics Analysis of a Micronutrient-Rich Dietary Pattern and the Aging Genotype 9p21 on the Plasma Proteome of Young Adults. Nutrients. 2025;17 (8):. doi: 10.3390/nu17081398. PubMed PMID:40284261 PubMed Central PMC12030164.
  10. Glenn, AJ, Tessier, AJ, Kavanagh, ME, Morgan, GA, Clish, CB, Salas-Salvado, J et al.. Metabolomic profiling of a cholesterol lowering plant-based diet from two randomized controlled feeding trials. Eur J Clin Nutr. 2025;79 (9):863-875. doi: 10.1038/s41430-025-01625-x. PubMed PMID:40263496 .
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Affiliations & Other Activities

  • Director, Clinical Nutrition and Risk Factor Modification Centre, St. Michael’s Hospital
  • Staff Physician, Division of Endocrinology, Department of Medicine, St. Michael’s Hospital
  • Professor and Canada Research Chair in Nutrition and Metabolism, Dept. of Medicine and Nutritional Sciences, Faculty of Medicine, University of Toronto
  • Canada Research Chair in Nutrition and Metabolism