Duminda N. Wijeysundera

MD, PhD, FRCPC, FAHA

Scientist

Biography

Dr. Duminda Wijeysundera is a Staff Physician in the Department of Anesthesia at St. Michael’s Hospital, a Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, and the Endowed Chair in Translational Anesthesiology Research at St. Michael’s Hospital and University of Toronto. He is also a Professor in the Department of Anesthesiology and Pain Medicine and the Institute of Health Policy Management and Evaluation at the University of Toronto, as well as a Senior Adjunct Scientist at ICES Central. Dr. Wijeysundera’s research program focuses on developing methods to better predict and prevent medical complications following major surgery. His program has generated more than 250 peer-reviewed publications, and received more than $5 million in peer-reviewed funding from the Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, and the Ontario government. In addition to his research activities, Dr. Wijeysundera is an Associate Editor at Anesthesiology, and a member of the editorial boards of Circulation and the Canadian Journal of Anesthesia.

Please note: Dr. Wijeysundera is not taking any summer students.

Recent Publications

  1. Li, B, Eisenberg, N, Beaton, D, Lee, DS, Al-Omran, L, Wijeysundera, DN et al.. Predicting 1-year successful clinical use of an arteriovenous access for hemodialysis using machine learning. NPJ Digit Med. 2025; :. doi: 10.1038/s41746-025-02187-9. PubMed PMID:41345783 .
  2. McIsaac, DI, Lee, S, Fergusson, D, Gillis, C, Khadaroo, RG, Meliambro, A et al.. Home-Based Prehabilitation for Older Surgical Patients With Frailty: A Randomized Clinical Trial. JAMA Surg. 2025; :. doi: 10.1001/jamasurg.2025.5288. PubMed PMID:41335421 PubMed Central PMC12676472.
  3. Venus, K, Wijeysundera, DN. Seeking guidance in preoperative cardiac assessment guidelines. Can J Anaesth. 2025; :. doi: 10.1007/s12630-025-03039-6. PubMed PMID:41326930 .
  4. Wijeysundera, DN, Alibhai, SMH, Puts, MTE, Xu, K, Daza, JF, Diep, C et al.. Significant new disability after major non-cardiac surgery in older adults aged 65 years and older in Canada: a multicentre prospective cohort study. Lancet Healthy Longev. 2025;6 (11):100789. doi: 10.1016/j.lanhl.2025.100789. PubMed PMID:41317744 .
  5. Philip, K, Jolly, A, Diep, C, Savage, RD, Wijeysundera, DN, Witiw, C et al.. Association of loneliness and social isolation with postoperative outcomes: a retrospective registry study. Br J Anaesth. 2025; :. doi: 10.1016/j.bja.2025.09.004. PubMed PMID:41136321 .
  6. Mbadjeu Hondjeu, AR, Zhao, ZY, Newton, L, Ajenkar, A, Termos, B, Shorr, R et al.. Large language models and their current use in perioperative medicine: a scoping review protocol. JBI Evid Synth. 2025;23 (10):2091-2103. doi: 10.11124/JBIES-25-00003. PubMed PMID:41017313 PubMed Central PMC12517723.
  7. Li, B, Eisenberg, N, Beaton, D, Lee, DS, Al-Omran, L, Wijeysundera, DN et al.. Reply. J Vasc Surg. 2025;82 (4):1545-1547. doi: 10.1016/j.jvs.2025.06.037. PubMed PMID:40967721 .
  8. Ladha, KS, Lee, J, Mattina, GF, Pazmino-Canizares, J, Wijeysundera, DN, Nezhad, FG et al.. Sustained mood improvement with laughing gas exposure (SMILE): a randomised, placebo-controlled pilot trial of nitrous oxide for treatment-resistant depression. BJPsych Open. 2025;11 (5):e208. doi: 10.1192/bjo.2025.10823. PubMed PMID:40936464 PubMed Central PMC12451564.
  9. Hua, M, BillingsIV, FT, Aziz, MF, Dutton, R, Kheterpal, S, Legrand, M et al.. Anesthesiology Clinical Trial Networks in the United States: A Report From the Anesthesia Research Council. Anesth Analg. 2025;141 (3):522-530. doi: 10.1213/ANE.0000000000007619. PubMed PMID:40816252 .
  10. Hua, M, Billings, FT 4th, Aziz, MF, Dutton, R, Kheterpal, S, Legrand, M et al.. Anesthesiology Clinical Trial Networks in the United States: A Report from the Anesthesia Research Council. Anesthesiology. 2025;143 (3):509-517. doi: 10.1097/ALN.0000000000005624. PubMed PMID:40793804 PubMed Central PMC12629501.
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Affiliations & Other Activities

  • Professor, Department of Anesthesia and Institute of Health Policy Management and Evaluation, University of Toronto
  • Staff Physician, Department of Anesthesia, St. Michael’s Hospital
  • Adjunct Scientist, ICES Central