Duminda N. Wijeysundera

MD, PhD, FRCPC, FAHA

Scientist

Biography

Dr. Duminda Wijeysundera is a Staff Physician in the Department of Anesthesia at St. Michael’s Hospital, a Scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital, and the Endowed Chair in Translational Anesthesiology Research at St. Michael’s Hospital and University of Toronto. He is also a Professor in the Department of Anesthesiology and Pain Medicine and the Institute of Health Policy Management and Evaluation at the University of Toronto, as well as a Senior Adjunct Scientist at ICES Central. Dr. Wijeysundera’s research program focuses on developing methods to better predict and prevent medical complications following major surgery. His program has generated more than 250 peer-reviewed publications, and received more than $5 million in peer-reviewed funding from the Canadian Institutes of Health Research, Heart and Stroke Foundation of Canada, and the Ontario government. In addition to his research activities, Dr. Wijeysundera is an Associate Editor at Anesthesiology, and a member of the editorial boards of Circulation and the Canadian Journal of Anesthesia.

Please note: Dr. Wijeysundera is not taking any summer students.

Recent Publications

  1. Mbadjeu Hondjeu, AR, Zhao, ZY, Newton, L, Ajenkar, A, Hladkowicz, E, Ladha, K et al.. Large language models in perioperative medicine-applications and future prospects: a narrative review. Can J Anaesth. 2025; :. doi: 10.1007/s12630-025-02980-w. PubMed PMID:40490617 .
  2. Li, B, Eisenberg, N, Beaton, D, Lee, DS, Al-Omran, L, Wijeysundera, DN et al.. Predicting mortality risk following major lower extremity amputation using machine learning. J Vasc Surg. 2025; :. doi: 10.1016/j.jvs.2025.03.198. PubMed PMID:40464726 .
  3. Diep, C, Jaffe, R, Witiw, C, Daza, JF, Wijeysundera, DN, Ravi, B et al.. Impact of major postoperative complications on employment and earnings after elective hip or knee replacement surgery: a population-based matched cohort study. Can J Anaesth. 2025;72 (5):738-747. doi: 10.1007/s12630-025-02960-0. PubMed PMID:40355799 .
  4. Botrel, T, Myles, PS, Futier, E, Garrigue, D, Bell, M, Egan, T et al.. A Delphi process to define medical reporting outcomes for urgent surgical pathways. Anaesth Crit Care Pain Med. 2025;44 (4):101529. doi: 10.1016/j.accpm.2025.101529. PubMed PMID:40288749 .
  5. Li, B, Aljabri, B, Beaton, D, Al-Omran, L, Hussain, MA, Lee, DS et al.. Predicting outcomes following open abdominal aortic aneurysm repair using machine learning. Sci Rep. 2025;15 (1):14362. doi: 10.1038/s41598-025-98573-0. PubMed PMID:40274999 PubMed Central PMC12022244.
  6. Li, B, Aljabri, B, Beaton, D, Hussain, MA, Lee, DS, Wijeysundera, DN et al.. Predicting Outcomes Following Carotid Artery Stenting Using Machine Learning. J Endovasc Ther. 2025; :15266028251333670. doi: 10.1177/15266028251333670. PubMed PMID:40249213 .
  7. Lee, S, Islam, N, Ladha, KS, Bicket, MC, Wijeysundera, DN. Prevention of hypotension after neuraxial anesthesia in nonobstetric surgery: a systematic review. Can J Anaesth. 2025;72 (5):721-737. doi: 10.1007/s12630-025-02925-3. PubMed PMID:40244359 .
  8. Bicket, MC, Ladha, KS, Haroutounian, S, McFarlin, K, Neff, M, McDuffie, RL et al.. Comparing Analgesic Regimen Effectiveness and Safety after Surgery (CARES): protocol for a pragmatic, international multicentre randomised trial. BMJ Open. 2025;15 (4):e099925. doi: 10.1136/bmjopen-2025-099925. PubMed PMID:40187774 PubMed Central PMC11973795.
  9. Lee, S, Diep, C, Wijeysundera, DN, Karthikeyan, V, Ladha, KS. The impact of substance use disorders on postoperative falls in major noncardiac surgery: A retrospective cohort analysis. J Clin Anesth. 2025;103 :111814. doi: 10.1016/j.jclinane.2025.111814. PubMed PMID:40120544 .
  10. Li, B, Eisenberg, N, Beaton, D, Lee, DS, Aljabri, B, Al-Omran, L et al.. Using Machine Learning to Predict Outcomes Following Thoracic and Complex Endovascular Aortic Aneurysm Repair. J Am Heart Assoc. 2025;14 (5):e039221. doi: 10.1161/JAHA.124.039221. PubMed PMID:40028848 PubMed Central PMC12132658.
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Affiliations & Other Activities

  • Professor, Department of Anesthesia and Institute of Health Policy Management and Evaluation, University of Toronto
  • Staff Physician, Department of Anesthesia, St. Michael’s Hospital
  • Adjunct Scientist, ICES Central