Jeffrey Perl

MD, FRCP(C), SM

Investigator

Biography

Dr Jeffrey Perl is a staff nephrologist at, St Michael’s Hospital in Toronto and Associate Professor of Medicine at the University of Toronto. He received his Master of Science in Epidemiology from The Harvard School for Public Health. He is a prior recipient of The John Maher Young Investigator Award by the International Society for Peritoneal Dialysis and has received several teaching awards at The University of Toronto and St. Michael’s Hospital. He serves as the current editor-in-chief of Peritoneal Dialysis International.  He is also chair of the home dialysis subcommittee of the American Society of Nephrology COVID-19 response team. His primary research interests and clinical practice focuses on improving the survival and quality of life for patients on home dialysis. Dr. Perl is a primary investigator in The International Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS) and principal investigator of the Optimizing the Prevention of Peritoneal Dialysis Associated Peritonitis in The United States (OPPUS) study.

Recent Publications

  1. Desbiens, LC, Tennankore, KK, Perl, J, Chan, CT, Nadeau-Fredette, AC. Frequency and Outcomes of Kidney Replacement Therapy Transitions in Canada. Kidney Int Rep. 2025;10 (4):1279-1282. doi: 10.1016/j.ekir.2025.01.008. PubMed PMID:40303225 PubMed Central PMC12034879.
  2. Wing, S, Ray, JG, Yau, K, Jeyakumar, N, Abdullah, S, Luo, B et al.. SGLT2 Inhibitors and Risk for Hyperkalemia Among Individuals Receiving RAAS Inhibitors. JAMA Intern Med. 2025; :. doi: 10.1001/jamainternmed.2025.0686. PubMed PMID:40293730 PubMed Central PMC12038716.
  3. Teitelbaum, I, Zhao, J, Tu, C, Bieber, B, Davies, S, Johnson, DW et al.. Associations Between Serum Sodium, Peritoneal Dialysis-Associated Peritonitis, and Mortality in the Peritoneal Dialysis Outcomes and Practice Patterns Study (PDOPPS). Am J Kidney Dis. 2025; :. doi: 10.1053/j.ajkd.2025.02.605. PubMed PMID:40220849 .
  4. Shah, A, El Shamy, O, Raker, CA, Perl, J, Hu, S. Impact of Dialysis Modality on Mortality and Complications in Cardiovascular Surgery: Insights from a National Retrospective Cohort Study. Kidney360. 2025; :. doi: 10.34067/KID.0000000701. PubMed PMID:40080732 .
  5. Lu, S, Merko, R, Gomez, D, Castillo, F, Perl, J. PD-associated peritonitis: Something's fishy. Perit Dial Int. 2025; :8968608241312751. doi: 10.1177/08968608241312751. PubMed PMID:39973066 .
  6. Shapiro, J, Schiff, J, Perl, J. Peritoneal dialysis and kidney transplantation: Your questions answered. Perit Dial Int. 2025; :8968608251313679. doi: 10.1177/08968608251313679. PubMed PMID:39871717 .
  7. McGrath, A, Perl, J, Brown, EA. Peritoneal Dialysis Modality Choice: Not an Automated Decision. Clin J Am Soc Nephrol. 2024;20 (2):311-3. doi: 10.2215/CJN.0000000627. PubMed PMID:39665583 PubMed Central PMC11835191.
  8. Tennankore, KK, McCullough, K, Bieber, B, Cho, Y, Johnson, DW, Kanjanabuch, T et al.. Prevalence and Outcomes of Chronic Kidney Disease-Associated Pruritus: International Results from Peritoneal Dialysis Outcomes and Practice Patterns Study. Clin J Am Soc Nephrol. 2024;19 (12):1622-1634. doi: 10.2215/CJN.0000000000000537. PubMed PMID:39652652 PubMed Central PMC11637705.
  9. Sakurada, T, Zhao, J, Tu, C, Bieber, B, Cheetham, M, Pisoni, RL et al.. Effects of initial peritoneal dialysis prescription on clinical outcomes in Japanese peritoneal dialysis patients: a cohort study. Sci Rep. 2024;14 (1):30109. doi: 10.1038/s41598-024-81934-6. PubMed PMID:39627492 PubMed Central PMC11614897.
  10. Shen, JI, Perl, J. Disparities in Care: Desperate for Modality Education. J Am Soc Nephrol. 2025;36 (1):16-18. doi: 10.1681/ASN.0000000578. PubMed PMID:39625792 PubMed Central PMC11706551.
Search PubMed

Affiliations & Other Activities

  • Nephrologist, Division of Nephrology, St. Michael’s Hospital
  • Assistant Professor of Medicine, University of Toronto
  • Chair, International Society of Nephrology’s Young Nephrologists Committee