Research Programs

Biography

Research Interests

Multiple sclerosis (MS), MRI biomarkers with clinical utility in prognostication and disease monitoring, cohort studies

Research Activities

Jiwon Oh is a staff neurologist, scientist, and Medical Director of the Barlo Multiple Sclerosis (MS) Program at St. Michael’s Hospital, University of Toronto. Dr. Oh’s research focuses on developing advanced MRI techniques in the spinal cord and brain for use in clinical settings. She leads the MRI research program at St. Michael’s Hospital, and is the principal investigator on numerous local and multi-center collaborative studies, including the Canadian Prospective Cohort Study to Understand Progression in MS (CanProCo), which is a national prospective cohort study designed to better understand progression in MS.

Recent Publications

  1. Laakso, SM, Oh, J, Raufdeen, F, Jones, A, Reiskanen, H, Feb, K et al.. Trigeminal neuralgia within the disease course of MS: Diagnostic and therapeutic implications from a multicenter cohort. Mult Scler. 2024; :13524585241309257. doi: 10.1177/13524585241309257. PubMed PMID:39727322 .
  2. Dal-Bianco, A, Oh, J, Sati, P, Absinta, M. Chronic active lesions in multiple sclerosis: classification, terminology, and clinical significance. Ther Adv Neurol Disord. 2024;17 :17562864241306684. doi: 10.1177/17562864241306684. PubMed PMID:39711984 PubMed Central PMC11660293.
  3. Androdias, G, Lünemann, JD, Maillart, E, Amato, MP, Audoin, B, Bruijstens, AL et al.. De-escalating and discontinuing disease-modifying therapies in multiple sclerosis. Brain. 2024; :. doi: 10.1093/brain/awae409. PubMed PMID:39707906 .
  4. Latypov, TH, Wolfensohn, A, Yakubov, R, Li, J, Srisaikaew, P, Jörgens, D et al.. Signatures of chronic pain in multiple sclerosis: a machine learning approach to investigate trigeminal neuralgia. Pain. 2024; :. doi: 10.1097/j.pain.0000000000003497. PubMed PMID:39680491 .
  5. Amin, M, Nakamura, K, Daboul, L, O'Donnell, C, Cao, Q, Rodrigues, P et al.. Incorporation of the central vein sign into the McDonald criteria. Mult Scler Relat Disord. 2024;93 :106182. doi: 10.1016/j.msard.2024.106182. PubMed PMID:39622133 .
  6. Keegan, BM, Absinta, M, Cohen-Adad, J, Flanagan, EP, Henry, RG, Klawiter, EC et al.. Spinal cord evaluation in multiple sclerosis: clinical and radiological associations, present and future. Brain Commun. 2024;6 (6):fcae395. doi: 10.1093/braincomms/fcae395. PubMed PMID:39611182 PubMed Central PMC11604059.
  7. Bsteh, G, Krajnc, N, Altmann, P, Hendin, B, Bharadia, T, Jaruszowic, S et al.. Treating to target in multiple sclerosis: Do we know how to measure whether we hit it?. Eur J Neurol. 2024;31 (12):e16526. doi: 10.1111/ene.16526. PubMed PMID:39445673 PubMed Central PMC11554867.
  8. Yeh, WZ, Van Der Walt, A, Skibina, OG, Kalincik, T, Alroughani, R, Kermode, AG et al.. Disease Activity in Pregnant and Postpartum Women With Multiple Sclerosis Receiving Ocrelizumab or Other Disease-Modifying Therapies. Neurol Neuroimmunol Neuroinflamm. 2024;11 (6):e200328. doi: 10.1212/NXI.0000000000200328. PubMed PMID:39442037 PubMed Central PMC11502106.
  9. Chen, L, Ren, Z, Clark, KA, Lou, C, Liu, F, Cao, Q et al.. Multicenter validation of automated detection of paramagnetic rim lesions on brain MRI in multiple sclerosis. J Neuroimaging. 2024;34 (6):750-757. doi: 10.1111/jon.13242. PubMed PMID:39410780 .
  10. Kalia, LV, Asis, A, Arbour, N, Bar-Or, A, Bove, R, Di Luca, DG et al.. Disease-modifying therapies for Parkinson disease: lessons from multiple sclerosis. Nat Rev Neurol. 2024;20 (12):724-737. doi: 10.1038/s41582-024-01023-0. PubMed PMID:39375563 .
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Affiliations & Other Activities

  • Staff Neurologist, Division of Neurology, Department of Medicine, St. Michael’s Hospital
  • Associate Professor, Department of Medicine, University of Toronto
  • Adjunct Faculty, Department of Neurology, Johns Hopkins University