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Manav Vyas

MBBS MSc PhD

Scientist, Li Ka Shing Knowledge Institute

Email: manav.vyas@mail.utoronto.ca
Tel: 416-864-5056

Research Programs

Biography

Dr. Vyas is a general neurologist and a clinician-scientist at the Li Ka Shing Knowledge Institute of St. Michael’s Hospital. He is an assistant professor at the University of Toronto in the Division of Neurology. He received academic training in India (medicine), Western University (epidemiology and biostatistics) and the University of Toronto (neurology, and clinical epidemiology and health care research). He has had multiple peer-reviewed publications in high-impact journals such as Neurology and Stroke. His work has been funded through the Heart and Stroke Foundation of Canada and the Canadian Institutes of Health Research.

His research evaluates and addresses inequalities in health, with a focus on neurological disorders, including stroke. He intends to build on his thesis work on immigrant health to study the influence of various social determinants of health on neurological health using linked administrative health data.

Recent Publications

  1. McNaughton, CD, Austin, PC, Jackevicius, CA, Chu, A, Holodinsky, JK, Hill, MD et al.. Incident prescriptions for common cardiovascular medications: comparison of recent versus pre-2020 medication adherence and discontinuation in three universal health care systems. BMC Cardiovasc Disord. 2025;25 (1):82. doi: 10.1186/s12872-025-04492-3. PubMed PMID:39910396 PubMed Central PMC11796216.
  2. Taghdiri, F, Vyas, MV, Kapral, MK, Lapointe-Shaw, L, Austin, PC, Gozdyra, P et al.. Access to Endovascular Thrombectomy: Does Driving Time to Comprehensive Stroke Center Matter More than Rurality?. Can J Neurol Sci. 2025; :1-21. doi: 10.1017/cjn.2025.15. PubMed PMID:39885832 .
  3. McNaughton, CD, Austin, PC, Chu, A, Santiago-Jimenez, M, Li, E, Holodinsky, JK et al.. Turbulence in the system: Higher rates of left-without-being-seen emergency department visits and associations with increased risks of adverse patient outcomes since 2020. J Am Coll Emerg Physicians Open. 2024;5 (6):e13299. doi: 10.1002/emp2.13299. PubMed PMID:39703807 PubMed Central PMC11655912.
  4. Austin, PC, Kapral, MK, Vyas, MV, Fang, J, Yu, AYX. Using Multilevel Models and Generalized Estimating Equation Models to Account for Clustering in Neurology Clinical Research. Neurology. 2024;103 (9):e209947. doi: 10.1212/WNL.0000000000209947. PubMed PMID:39393031 PubMed Central PMC11469681.
  5. Vyas, MV, Chen, R, Campitelli, MA, Odugbemi, T, Sharpe, I, Chu, JY et al.. Neurological Events Following COVID-19 Vaccination: Does Ethnicity Matter?. Can J Neurol Sci. 2024; :1-4. doi: 10.1017/cjn.2024.299. PubMed PMID:39358974 .
  6. Vyas, MV, Rijal, H, Yu, AYX, Austin, PC, Chu, A, Santiago-Jimenez, M et al.. Association Between Neighborhood-Level Income and the Incidence of Cardiovascular Events Varies by Immigration Status: A Population-Based Cohort Study. J Am Heart Assoc. 2024;13 (19):e036511. doi: 10.1161/JAHA.124.036511. PubMed PMID:39344632 PubMed Central PMC11681456.
  7. Lee, S, Marrie, RA, Fadda, G, Freedman, MS, Lee, L, Muccilli, A et al.. Is there a prodrome to NMOSD? An investigation of neurologic symptoms preceding the first NMOSD attack. Mult Scler. 2024;30 (11-12):1423-1435. doi: 10.1177/13524585241275491. PubMed PMID:39258406 PubMed Central PMC11529114.
  8. Rotstein, DL, Freedman, MS, Konig, A, Lee, L, Luo, J, Maxwell, C et al.. Investigation of health care use and a possible prodrome before the first attack in NMOSD and MOGAD. Mult Scler. 2024;30 (10):1331-1340. doi: 10.1177/13524585241272939. PubMed PMID:39234853 PubMed Central PMC11457589.
  9. Vyas, MV, Saposnik, G, Yu, AYX, Austin, PC, Chu, A, Alonzo, R et al.. Association Between Immigration Status and Ambulatory Secondary Stroke Preventive Care in Ontario, Canada. Neurology. 2024;103 (1):e209536. doi: 10.1212/WNL.0000000000209536. PubMed PMID:38861692 .
  10. Vyas, MV, Kapral, MK, Alonzo, R, Fang, J, Rotstein, DL. Proportion of Life Spent in Canada and the Incidence of Multiple Sclerosis in Permanent Immigrants. Neurology. 2024;102 (10):e209350. doi: 10.1212/WNL.0000000000209350. PubMed PMID:38657190 .
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Affiliations & Other Activities

  • ICES Adjunct Scientist