❮ Back to Researchers

Matthew Muller

MD, FRCPC, PhD

Investigator

Email: Matthew.Muller@unityhealth.to
Tel: 416-864-6060 Ext 3563

Biography

Dr. Matthew Muller is an infectious diseases physician and the Medical Director of Infection Prevention and Control at Unity Health Toronto. He is an Associate Professor at the University of Toronto in the Department of Medicine. His research interests are focused on the epidemiology and previous of hospital-acquired infections including C. difficile, infections due to common antibiotic-resistant organisms and emerging infectious threats such as MERS-CoV and SARS-CoV2. Dr. Muller has a particular interest in hand hygiene measurement and improvement including the use of novel technological approaches to hand hygiene improvement. Dr. Muller chairs the Provincial Infectious Diseases Advisory Committee on Infection Prevention and Control, and is also interested in guideline and policy development with respect to infection prevention for Ontario hospitals.

Recent Publications

  1. Soe, P, Muller, MP, Sadarangani, M, Kellner, JD, Vanderkooi, OG, Naus, M et al.. Safety of co-administration of COVID-19 and seasonal influenza vaccines in individuals with autoimmune diseases from the Canadian National Vaccine Safety Network. Hum Vaccin Immunother. 2025;21 (1):2560172. doi: 10.1080/21645515.2025.2560172. PubMed PMID:40963477 PubMed Central PMC12452431.
  2. Williams, V, Schwartz, KL, Brown, K, Muller, M, Powis, J, Ricciuto, D et al.. Risk mitigation of shared room ventilation and filtration on SARS-CoV-2 transmission: a multicenter test-negative study. Infect Control Hosp Epidemiol. 2025;46 (10):1-7. doi: 10.1017/ice.2025.10256. PubMed PMID:40928142 PubMed Central PMC12615120.
  3. Coleman, BL, Robertson, NM, Harrison, RA, Valiquette, L, Langley, JM, Muller, MP et al.. Risk factors for infection with SARS-CoV-2 in a cohort of Canadian healthcare workers: 2020-2023. Epidemiol Infect. 2025;153 :e72. doi: 10.1017/S0950268825100101. PubMed PMID:40548383 PubMed Central PMC12188280.
  4. Dabaja-Younis, H, Kandel, C, Green, K, Johnstone, J, Zhong, Z, Kassee, C et al.. Invasive Group A Streptococcal Infection in Children, 1992-2023. JAMA Netw Open. 2025;8 (4):e252861. doi: 10.1001/jamanetworkopen.2025.2861. PubMed PMID:40168022 PubMed Central PMC11962665.
  5. Soe, P, Vanderkooi, OG, Sadarangani, M, Naus, M, Muller, MP, Kellner, JD et al.. mRNA COVID-19 vaccine safety among children and adolescents: a Canadian National Vaccine Safety Network cohort study. Lancet Reg Health Am. 2024;40 :100949. doi: 10.1016/j.lana.2024.100949. PubMed PMID:39659558 PubMed Central PMC11629564.
  6. Top, KA, Shulha, HP, Muller, MP, Valiquette, L, Vanderkooi, OG, Kellner, JD et al.. Participant-reported neurological events following immunization in the Canadian National Vaccine Safety Network-COVID-19 vaccine (CANVAS-COVID) study. Vaccine. 2024;42 (26):126445. doi: 10.1016/j.vaccine.2024.126445. PubMed PMID:39413493 .
  7. Jiang, L, Muller, M, McGeer, A, Simor, A, Holness, DL, Coleman, KKL et al.. Assessing a safety climate tool adapted to address respiratory illnesses in Canadian hospitals. Antimicrob Steward Healthc Epidemiol. 2024;4 (1):e157. doi: 10.1017/ash.2024.426. PubMed PMID:39371440 PubMed Central PMC11450664.
  8. Coleman, BL, Gutmanis, I, Bondy, SJ, Harrison, R, Langley, J, Fischer, K et al.. Canadian health care providers' and education workers' hesitance to receive original and bivalent COVID-19 vaccines. Vaccine. 2024;42 (24):126271. doi: 10.1016/j.vaccine.2024.126271. PubMed PMID:39226785 .
  9. Soe, P, Sadarangani, M, Naus, M, Muller, MP, Vanderkooi, OG, Kellner, JD et al.. Impact of recruitment strategies on individual participation practices in the Canadian National Vaccine Safety Network: prospective cohort study. Front Public Health. 2024;12 :1385426. doi: 10.3389/fpubh.2024.1385426. PubMed PMID:39188790 PubMed Central PMC11345188.
  10. Soe, P, Wong, H, Naus, M, Muller, MP, Vanderkooi, OG, Kellner, JD et al.. mRNA COVID-19 vaccine safety among older adults from the Canadian National Vaccine Safety Network. Vaccine. 2024;42 (18):3819-3829. doi: 10.1016/j.vaccine.2024.04.096. PubMed PMID:38714447 .
Search PubMed

Affiliations & Other Activities

  • Medical Director, Infection Prevention and Control, St. Michael’s Hospital
  • Assistant Professor, Department of Medicine, University of Toronto